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Johnna D Wesley Selected Research

Antigens

1/2022Induction of antigenic immune tolerance to delay type 1 diabetes - challenges for clinical translation.
8/2021Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
8/2021Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
1/2021Overcoming Obstacles in the Development of Antigen-Specific Immunotherapies for Type 1 Diabetes.
1/2018Low HLA binding of diabetes-associated CD8+ T-cell epitopes is increased by post translational modifications.
5/2014CD8 T-cell reactivity to islet antigens is unique to type 1 while CD4 T-cell reactivity exists in both type 1 and type 2 diabetes.
4/2012An overview of sipuleucel-T: autologous cellular immunotherapy for prostate cancer.

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Johnna D Wesley Research Topics

Disease

12Type 1 Diabetes Mellitus (Autoimmune Diabetes)
11/2022 - 10/2010
3Autoimmune Diseases (Autoimmune Disease)
08/2021 - 01/2018
3Disease Progression
01/2019 - 10/2010
1Diabetic Nephropathies (Diabetic Nephropathy)
01/2024
1Renal Insufficiency (Renal Failure)
01/2024
1Chronic Renal Insufficiency
01/2024
1Albuminuria
01/2024
1Acquired Immunodeficiency Syndrome (AIDS)
11/2022
1Hyperglycemia
01/2018
1Type 2 Diabetes Mellitus (MODY)
05/2014
1Neoplasms (Cancer)
04/2012
1Prostatic Neoplasms (Prostate Cancer)
04/2012
1Infections
07/2008

Drug/Important Bio-Agent (IBA)

7AntigensIBA
01/2022 - 04/2012
5Insulin (Novolin)FDA Link
08/2021 - 10/2010
4Biomarkers (Surrogate Marker)IBA
01/2021 - 11/2015
3CytokinesIBA
11/2022 - 08/2021
3AutoantibodiesIBA
01/2021 - 10/2010
2InterleukinsIBA
08/2021 - 08/2021
2Transforming Growth Factor beta (TGF-beta)IBA
08/2021 - 08/2021
1GoldIBA
01/2024
1preproinsulinIBA
11/2022
1LiraglutideFDA Link
11/2022
1Insulin-Like PeptidesIBA
01/2020
1Peptides (Polypeptides)IBA
01/2018
1Proteins (Proteins, Gene)FDA Link
01/2018
1Pork Regular Insulin (Velosulin)FDA Link
01/2018
1EpitopesIBA
01/2018
1InsulinsIBA
11/2015
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2014
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
04/2012
1prostatic acid phosphataseIBA
04/2012
1Recombinant ProteinsIBA
04/2012
1sipuleucel-T (APC8015)FDA Link
04/2012
1Interleukin-4 (Interleukin 4)IBA
07/2008

Therapy/Procedure

6Immunotherapy
01/2022 - 04/2012
2Therapeutics
01/2019 - 01/2014
1Precision Medicine
01/2024
1Injections
11/2015